isomorph.js is an 11kb minified zero dependency masonry layout system, inspired by isotope, that has no dependencies.

The term Masonry layout probably owes its name to the popular jQuery Masonry plugin that is used to generate this type of layout. Masonry layout is also referred to as the Pinterest Style Layout, as www.pinterest.com was the first major website to use this layout style. Masonry is a grid layout based on columns.
It allows a layout system with equal widths that can expand to fill their container. The panels can then be sorted, grouped and/or filtered. It also handles lazy loading of images if requested.

This layout is used widely now in many websites for blogs etc.

This particular plugin is small, fast and versatile. 11kb is the minified size, 5kb gzipped.